Are de novo rea(21;21) chromosomes really de novo?

نویسندگان

  • Bérénice Hervé
  • Thibaud Quibel
  • Stéphane Taieb
  • Mireille Ruiz
  • Denise Molina-Gomes
  • François Vialard
چکیده

We report a rare case of recurrent trisomy 21 caused by an isochromosome 21q and what is very likely to be maternal germ-line cell mosaicism. Over 90% of cases of rob(21;21) reported in the literature are due to an isochromosome 21q, with a risk of recurrence of more than 10%.

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عنوان ژورنال:

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2015